Price spread for CPT 45380: Hospital pricing ranges from $806 to $3,678. Compared with Medicare ($308), this is roughly 3x-12x.
What Is a Colonoscopy with Biopsy?
Colonoscopy with biopsy examines the colon and removes tissue samples for diagnosis.
When Is It Ordered?
Doctors commonly order this for cancer screening, bleeding, abnormal stool tests, and chronic GI symptoms.
How Long Does It Take?
30-60 minutes plus recovery.
How to Prepare
Full bowel prep is required. Arrange a ride home.
How to Save on a Colonoscopy w/ Biopsy
Potential savings: 20-50% by comparing facilities before scheduling.
- Request the CPT-specific cash rate and negotiated estimate.
- Ask whether any part can be done in a lower-cost outpatient setting.
- Verify in-network status and pre-authorization requirements.
Hospital Prices for CPT 45380
Table below shows a sample of hospitals with reported prices for this procedure.
| Hospital | City | State | Cash Price | Negotiated | Gross Charge |
|---|---|---|---|---|---|
| VIBRA HOSPITAL OF AMARILLO, LLC | AMARILLO | TX | N/A | $2 | N/A |
| VIBRA HOSPITAL OF FARGO LLC | FARGO | ND | N/A | $5 | N/A |
| VIBRA HOSPITAL OF DENVER LLC | THORNTON | CO | N/A | $8 | N/A |
| BRISTOL HOSPITAL INCORPORATED | BRISTOL | CT | $21 | N/A | $256 |
| UNIVERSAL HEALTH SERVICES OF RANCHO SPRINGS INC | MURRIETA | CA | N/A | $30 | N/A |
| ST LUKES METHODIST HOSPITAL | CEDAR RAPIDS | IA | N/A | N/A | $40 |
| VIBRA OF SOUTHEASTERN MICHIGAN LLC | TAYLOR | MI | N/A | $42 | N/A |
| SHANNON MEDICAL CENTER | SAN ANGELO | TX | $57 | $73 | $115 |
| MOUNTAIN RIVER BIRTHING AND SURGERY CENTER LLC | BLACKFOOT | ID | $72 | $888 | $103 |
| CROUSE HEALTH HOSPITAL INC | SYRACUSE | NY | $98 | $88 | $98 |
| PUBLIC HOSPITAL DISTRICT NO 2 SKAGIT COUNTY WASHINGTON | ANACORTES | WA | N/A | $116 | $798 |
| DOCTORS HOSPITAL OF LAREDO | LAREDO | TX | N/A | $155 | N/A |
| FORT DUNCAN MEDICAL CENTER, L.P. | EAGLE PASS | TX | N/A | $155 | N/A |
| AUBURN COMMUNITY HOSPITAL | AUBURN | NY | $174 | N/A | N/A |
| TRI-CITY HOSPITAL | OCEANSIDE | CA | N/A | $188 | $436 |
| ADVENTIST HEALTH SYSTEM-SUNBELT INC | WAUCHULA | FL | N/A | $200 | N/A |
| SWEDISHAMERICAN HOSPITAL | ROCKFORD | IL | $205 | $976 | $1,205 |
| MOBILE INFIRMARY ASSOCIATION | MOBILE | AL | N/A | $213 | N/A |
| HENDRICKS COUNTY HOSPITAL | DANVILLE | IN | $216 | $369 | $618 |
| MINIMALLY INVASIVE SURGERY HOSPITAL | LENEXA | KS | $216 | $369 | $618 |
| HOLLAND COMMUNITY HOSPITAL | HOLLAND | MI | $228 | $353 | $380 |
| FAYETTE MEDICAL CENTER | FAYETTE | AL | $232 | $255 | $387 |
| PROFESSIONAL RESOURCES MANAGEMENT PSYCHIATRIC SERVICES, LLC | LUVERNE | AL | $232 | $255 | $387 |
| VIBRA HOSPITAL OF WESTERN MASSACHUSETTS LLC | ROCHDALE | MA | N/A | $260 | N/A |
| AGH LAVEEN LLC | LAVEEN | AZ | N/A | $330 | $1,982 |
| LANCASTER HOSPITAL CORPORATION | PALMDALE | CA | N/A | $330 | N/A |
| TEMECULA VALLEY HOSPITAL, INC. | TEMECULA | CA | N/A | $330 | N/A |
| GALENCARE, INC. | SAINT PETERSBURG | FL | N/A | $333 | N/A |
| NORTHSIDE HOSPITAL INC | LAWRENCEVILLE | GA | N/A | $333 | N/A |
| PAULDING MEDICAL CENTER, INC. | HIRAM | GA | N/A | $333 | N/A |
| SARASOTA DOCTORS HOSPITAL INC | SARASOTA | FL | N/A | $333 | N/A |
| SPARKS FAMILY HOSPITAL INC | SPARKS | NV | N/A | $333 | N/A |
| KANSAS SURGERY & RECOVERY CENTER LLC | WICHITA | KS | $336 | N/A | $3,119 |
| MORTON COUNTY HOSPITAL | ELKHART | KS | $342 | N/A | N/A |
| EAST CARROLL PARISH HOSPITAL | LAKE PROVIDENCE | LA | $343 | $366 | $457 |
| MARIN GENERAL HOSPITAL | GREENBRAE | CA | $350 | N/A | $354 |
| MEMORIAL HOSPITAL, INC. | MANCHESTER | KY | N/A | $353 | N/A |
| REID HOSPITAL & HEALTH CARE SERVICES INC | RICHMOND | IN | N/A | $353 | N/A |
| UNIVERSITY MEDICAL CENTER, INC | LOUISVILLE | KY | N/A | $353 | N/A |
| BAYHEALTH MEDICAL CENTER, INC | DOVER | DE | $370 | $204 | N/A |
| BAYHEALTH MEDICAL CENTER, INC | MILFORD | DE | $370 | $204 | $2,690 |
| DOCTORS MEMORIAL HOSPITAL INC | PERRY | FL | $384 | $376 | $640 |
| SOUTH BROWARD HOSPITAL DISTRICT | PEMBROKE PINES | FL | $384 | $376 | $640 |
| THE PAVILION AT HEALTHPARK LLC | FORT MYERS | FL | $384 | $376 | $640 |
| APOLLO BEHAVIORAL HEALTH HOSPITAL LLC | BATON ROUGE | LA | N/A | $385 | N/A |
| APPALACHIAN REGIONAL HEALTHCARE INC | HARLAN | KY | N/A | $385 | N/A |
| DEACONESS WOMENS HOSPITAL OF SOUTHERN INDIANA LLC | NEWBURGH | IN | N/A | $385 | N/A |
| STONEBRIDGE HEALTH SYSTEMS LLC | CAMERON | LA | N/A | $385 | N/A |
| MORRIS HOSPITAL | MORRIS | IL | $389 | $1,150 | $1,437 |
| ELADH LP | LOS ANGELES | CA | $411 | $105 | $2,161 |
| BAXTER COUNTY REGIONAL HOSPITAL INC | MOUNTAIN HOME | AR | N/A | $431 | N/A |
| COMMUNITY HOSPITAL INC | TALLASSEE | AL | N/A | $431 | N/A |
| CONWAY REGIONAL MEDICAL CENTER INC | CONWAY | AR | N/A | $431 | N/A |
| FORREST CITY ARKANSAS HOSPITAL COMPANY, LLC | FORREST CITY | AR | N/A | $431 | N/A |
| BBH BMC LLC | BIRMINGHAM | AL | $433 | $106 | $2,276 |
| HC PARTNERSHIP | BIRMINGHAM | AL | $433 | $106 | $2,276 |
| UNIVERSITY OF KENTUCKY | LEXINGTON | KY | $438 | N/A | $220 |
| UHS OF TEXOMA INC | DENISON | TX | N/A | $438 | N/A |
| MIAMI JEWISH HEALTH SYSTEMS INC | MIAMI | FL | $469 | $275 | $469 |
| KAISER FOUNDATION HOSPITALS | MANTECA | CA | $532 | $106 | $2,801 |
| PRIME HEALTHCARE SERVICES - GARDEN GROVE LLC | GARDEN GROVE | CA | $532 | $106 | $2,801 |
| VICTOR VALLEY HOSPITAL ACQUISITION INC | VICTORVILLE | CA | N/A | N/A | $532 |
| OCALA BEHAVIORAL HEALTH LLC | OCALA | FL | N/A | $539 | $3,600 |
| ADVANCED CARE HOSPITAL OF WHITE COUNTY | SEARCY | AR | N/A | $545 | N/A |
| BAPTIST HEALTH | LITTLE ROCK | AR | N/A | $545 | N/A |
| HONORHEALTH | PHOENIX | AZ | N/A | $569 | N/A |
| WOODRIDGE OF WEST MEMPHIS, LLC | WEST MEMPHIS | AR | N/A | $569 | N/A |
| BARBARA ANN KARMANOS CANCER HOSPITAL | DETROIT | MI | $572 | $633 | $1,144 |
| AURORA BEHAVIORAL HEALTHCARE - TEMPE, LLC | TEMPE | AZ | N/A | $582 | N/A |
| UNITED METHODIST BEHAVIORAL HEALTH SYSTEM, INC | MAUMELLE | AR | N/A | $582 | N/A |
| THOREK MEMORIAL HOSPITAL | CHICAGO | IL | N/A | N/A | $594 |
| DISTRICT HOSPITAL PARTNERS L P | WASHINGTON | DC | N/A | $596 | N/A |
| BANNER BAYWOOD MEDICAL CENTER | MESA | AZ | N/A | $597 | N/A |
| BANNER IRONWOOD MEDICAL CENTER | QUEEN CREEK | AZ | N/A | $597 | N/A |
| BAPTIST HEALTH | LITTLE ROCK | AR | N/A | $597 | N/A |
State-by-State Pricing for Colonoscopy w/ Biopsy
Explore where hospitals in each state report prices for CPT 45380.
Alabama
Alaska
Arizona
Arkansas
California
Colorado
Connecticut
Delaware
District of Columbia
Florida
Georgia
Hawaii
Idaho
Illinois
Indiana
Iowa
Kansas
Kentucky
Frequently Asked Questions
How much does a Colonoscopy w/ Biopsy cost without insurance?
Based on published hospital data, Colonoscopy w/ Biopsy prices typically range from $806 to $3,678. Always ask for the self-pay or cash rate before scheduling.
Why do Colonoscopy w/ Biopsy prices vary so much by hospital?
Hospitals negotiate different payer contracts, apply different facility fees, and use different chargemaster pricing strategies. That creates large price gaps for the same CPT code.
What does Medicare pay for CPT 45380?
In this dataset, the Medicare facility reference is $308 for CPT 45380.
How can I lower my Colonoscopy w/ Biopsy bill?
Compare multiple facilities, ask for the cash price up front, and request a written estimate with all facility and professional fees.
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